Russian President Vladimir Putin during a national address Wednesday threatened the use of nuclear weapons in the country's conflict against Ukraine, in a speech that has exposed Russia's disastrous war against its neighbors where a recent Ukrainian offensive has led to massive gains for the defenders. In the bellicose speech, Mr. Putin said, “Russia will use all the instruments at its disposal to counter a threat against its territorial integrity—this is not a bluff."  The Russian strongman accused the leaders of the North Atlantic Treaty Organization, or NATO, of concluding that it would be acceptable to use nuclear weapons against Russia. Mr. Putin did not provide any proof that his remarks were factual.  “To those who allow themselves such statements, I would like to remind them, Russia also has many types of weapons of destruction, the…